8.7 Renal Impairment The pharmacokinetics of hydromorphone are influenced by renal impairment. Start people with renal impairment on 1-fourth to one-half the usual starting up dose with regards to the degree of impairment. fentanyl intranasal and hydromorphone equally improve sedation. Prevent or Use Alternate Drug. Restrict use to individuals for https://geralde654qwa0.daneblogger.com/profile