Ninety% of ibuprofen is metabolised to inactive compounds from the liver, mostly by glucuronidation, to create two metabolites - a hydroxylated compound as well as a carboxylated compound. Evident quantity of distribution is 0.fourteen L/kg. Ibuprofen and its metabolites quickly cross the placental barrier in Expecting animals (rabbits and rats). https://wayneg555gar7.wikiexcerpt.com/user