Pentobarbital will decrease the level or effect of hydrocortisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Older adults or those with chronic medical conditions may experience depression, confusion, or excitement after taking the drug. pentobarbital will decrease the level or effect of pantoprazole by affecting hepatic/intestinal enzyme CYP3A4 met... https://bookmarkstime.com/story20913413/fascination-circa-pentobarbital-effects